The 'ESE API' returned 'Unable to perform the operation. Either you can not connect to the specified server
or the service you are trying to connect to is not running.
' from a call to 'HrESEBackupRestoreNodes()' additional data ''
You will see a few of these messages in your event log before the actual backup starts if you are performing an online backup of a remote Exchange Server and have the Exchange Admin software installed.
These error messages seem to be logged because no Exchange server is running on the local machine and can be ignored. Simply verify that you see a later informational event log message confirming the successful backup of the information store.